ISSN: 0000-0000
Gore N.1 , Sangale B.2
1Associate Professor, Department of Agadtantra, VEWS’s Ahinsa Institute of Ayurveda, Dondaicha Dist. Dhule
2Associate Professor, Department of Samhita Siddhant, VEWS’s Ahinsa Institute of Ayurveda, Dondaicha Dist. Dhule
Date of Acceptance: 2026-03-23
Date of Publication:2026-04-13
Correspondence Address:
Keywords: Nasya Karma, Urdhvajatrugata Roga, Intranasal Drug Delivery, Preventive & Promotive Treatment
Source of Support: Nill
Conflict of Interest: Non declared
Classical texts emphasize the nose as the gateway to the head, enabling direct drug delivery to cranial structures. Urdhvajatrugata roga comprises diseases affecting structures above the clavicle, including the nose, eyes, ears, brain, and throat. Ayurveda described Nasya Karma (nasal administration of medicated oils, ghrita or churna) as a principal therapeutic and preventive intervention for these disorders. Contemporary research supports this view by demonstrating that intranasal administration can bypass hepatic first-pass metabolism and even the blood–brain barrier. This paper reviews classical Ayurvedic concepts alongside modern scientific evidence to evaluate the preventive and promotive roles of Nasya. Evidence suggests that Nasya contributes to neuroprotection, mucosal immunity, improved cognitive function, and disease prevention in the head and neck region.