Correspondence Address:
Dr. Ashvini Vishnu Bagade Medical Officer, All India Institute of Ayurveda, Goa. Email - ashvinibagade95@gmail.com
Date of Acceptance: 2025-08-30
Date of Publication:2025-09-27
Article-ID:IJIM_442_09_25 https://ijim.co.in
Source of Support: Nil
Conflict of Interest: Non declared
How To Cite This Article: Bagade A. Scientific Review on Mode of Action of Virechana Karma with Reference to Various Skin Disorders. Int J Ind Med 2025;6(09):117 -123 DOI: http://doi.org/10.55552/IJIM.2025.60921
Virechana Karma (therapeutic purgation) is a cornerstone of Panchakarma, the bio-purification modality in Ayurveda. It is specifically indicated for disorders stemming from the vitiation of Pitta and Rakta (blood), which are fundamental to the pathogenesis of many skin diseases. This review aims to synthesize the classical Ayurvedic understanding and contemporary clinical evidence regarding the mode of action of Virechana Karma in managing skin disorders like psoriasis (Ek Kushtha), eczema (Vicharchika), acne vulgaris (Yauvan Pidika), and vitiligo (Shwitra). The procedure works through a multi-faceted mechanism involving the purification of microchannels (Srotas), correction of Agni (digestive and metabolic fire), elimination of morbid Doshas (bio-humors) from the deepest tissues, and restoration of homeostasis. Clinical case studies have demonstrated significant efficacy, with reports of 50-80% improvement in symptoms. This article concludes that Virechana Karma offers a comprehensive, systemic detoxification approach that addresses the root cause of stubborn skin diseases, making it a highly effective therapeutic intervention.
Keywords: Virechana Karma, Panchakarma, Skin Diseases, Psoriasis, Ek Kushtha, Mode of Action.