Abstract

Abstract

Background: Ayurveda emphasizes prevention as the primary goal of healthcare, and Agadtantra extends this principle into toxicology by focusing on early detection and avoidance of toxic exposures. In the modern era, increasing environmental and synthetic toxin exposure contributes significantly to both acute and chronic diseases. Objective: To critically analyze preventive toxicological principles described in Sushruta Samhita Kalpa Sthana Chapter 1 and correlate them with contemporary toxicology and disease manifestations. Materials and Methods: A qualitative classical textual analysis of Sushruta Samhita Kalpa Sthana Chapter 1 with Dalhana commentary was conducted. Concepts were categorized into exposure pathways, manifestations, diagnostic methods, and preventive strategies, and interpreted in light of modern toxicological science. Results: Sushruta’s descriptions of exposure pathways, clinical features, and diagnostic approaches correspond closely with modern understanding of toxic exposure and disease causation. Preventive strategies demonstrate strong alignment with current preventive health principles. Conclusion: Agadtantra provides a comprehensive and practical framework for preventive toxicology, highly relevant in addressing contemporary environmental and lifestyle-related diseases.