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International Journal of Indian Medicine
IIFS Impact Factor: 2.125

ISSN: 2582-7634

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Review Article


Year: 2023 |Volume: 4 | Issue: 12 |Pages: 06-15


CRITICAL REVIEW ON HARIDRAKHANDA WITH SPECIAL REFERENCE TO URTICARIA

About Author

Rathava P.1 , Bedarkar P.2 , Patgiri B.3

1Assistant Professor in RSBK Department, K.J Institute of Ayurveda and Research, Savli, Vadodara.

2Associate Professor in RSBK Department, ITRA, Jamnagar

3HOD in RSBK Department, ITRA, Jamnagar.

Correspondence Address:

Dr. Priti Rathava (BAMS, MD) Assistant Professor in RSBK Department, K.J Institute of Ayurveda and Research,Savli, Vadodara. Email: pritir737@gmail.com Mob.no.:6353245133

Date of Acceptance: 2023-11-30

Date of Publication:2024-01-12

Article-ID:IJIM_277_01_24 http://ijim.co.in

Source of Support: Nill

Conflict of Interest: None declared

How To Cite This Article: Rathava P. Bedarkar P. Patgiri B. Critical Review on Haridrakhanda with Special Reference to Urticaria. Int J Ind Med 2023;4(12):06-15. DOI: http://doi.org/10.55552/IJIM.2023.41202

Abstract

Background: Urticaria is recurrent, transient, cutaneous swelling and erythema which resolves within 24 hours without leaving residual cutaneous signs. Approximately 15 to 20% of the general population will have urticaria at least once during their lifetime. Haridrakhanda is one such formulation mentioned in classical text books specially indicated for curing Sheetapitta, Udarda, Kotha etc. A detailed literature survey has been conducted to explore the probable mode of action of Haridrakhanda in Sheetapitta. Most of the ingredients are having Immunomodulatory, antifungal, anti-bacterial, antioxidative and anti-inflammatory activity may work on Sheetapitta. Apart from the ingredients of the formulation are predominant with Katu, Tikta, Kashaya, Madhura Rasa, Ushna Virya, Katu and Madhura Vipaka and Kapha Pitta or Tridosha Shamaka qualities. All the contents of Haridrakhanda are having properties to control the allergic condition and improve Vyadhikshamatva (Immunomodulatory).

Keywords: Haridrakhanda, Sheetapitta

Introduction

Sheetapitta (Urticaria) is one of the common dermatoses found all over the world, showing a definite rise in its incidence day by day. The exact incidence and prevalence of chronic urticaria are not known, although it occurs in at least 0.1% and possibly up to 3% of the population.1 Urticaria is not a life-threatening disorder, but it makes worried the patient due to its appearance, severe itching disturbing routine and its chronic nature. In other cases, it manifests as part of a spectrum of systemic anaphylaxis, which may be life threatening. The classical Ayurvedic literature has got ample references and description of disease in reference under the names- Sheetapitta, Udarda & Kotha. Sheetapitta suggests the involvement of Vata and Pitta Dosha along with Rasa and Rakta Dhatu. ‘Sheetapitta-Udarda-Kotha’ can be co-related with Urticaria as they have similar symptomatology i.e. Varatidamshta Samsthana Shotha means the nettle rash, Kandu etc. The western thinkers have considered it is an allergic condition. The elevated histamine level has been given more importance and as such antihistaminic drugs are the drug of choice to combat against urticaria. The recovery in most cases is only partial and inadequate. With all advancement of modern medical science in all directions and minutia, including dermatology, there are still many skin diseases which have no specific treatment and urticaria is one of them. Haridrakhanda is an effective formulation for the management of Sheetapitta, Udarda, Kotha etc.2 Haridra is effective drug for the management of skin disorders including Sheetapitta, Udarda, Kotha etc. and it is included in several classified group of drugs like Kushthaghnadashemani, Vishaghna-Mahakashaya and said to possess Kandughna property.3 Very few references were found from Samhita hence there are three reference of Haridrakhanda mentioned in classical textbook of Bhaishjya Ratnavali.

Method of Preparation:

  • 8 parts Haridra powder was taken in to s.s vessel and 6 parts Goghrita was added. And heating was continued in mild fire, over gas stove. Thus, frying of Harida in Ghrita was done.
  • Then, 64 parts Godugdha and 50 parts Sharkara was added and stirring was done until sugar was dissolve in the mixture.
  • Heating was carried out till the mixture attained desired consistency.
  • The vessel was removed from the fire and stirred continuously to reduce the temperature. When the temperature was reduced to 75-800C, fine powder of Prakshepa  Dravyas were added and stirred well to get a homogenous blend.
  • The blended mass was passed through 10# sieve to obtain granules, dried at room temperature. Granules were packed in airtight containers.

Methodology: The study was done by in-depth literature survey through various Ayurveda classical text books, various journals and articles. Review mainly focused on the pharmacological properties of each ingredient in modern as well as Ayurvedic perspectives.

Most of the ingredients are having Immunomodulatory, antifungal, anti-bacterial, antioxidative and anti-inflammatory activity.

Pharmacological properties in Ayurvedic perspective: As per Ayurveda principles, pharmacological actions of a drug can be inferred through Rasadi Panchaka and classical categorization of drugs. 

Here for the review, reference of Haridrakhanda was taken from B.R. (55/13-17). It is apparent from (Table no.3), the ingredients of the formulation are predominant with Katu, Tikta, Kashaya, Madhura Rasa, Ushna Virya, Katu and Madhura Vipaka and Kapha Pitta / Tridosha Shamaka qualities. All the contents of Haridrakhanda are having properties to control the allergic condition and improve Vyadhikshamatva (Immunomodulatory). Katu Rasa, Laghu, Ruksha and Tikshna Guna, Ushna Virya and Katu Vipaka properties of these drugs will eliminates the aggravating Vata and Kapha dosha which leading to Samprapti Vighatana. And the ingredients are capable of bringing back the normalcy of vitiated Dosha in Sheetapitta. Owing to the Kanduhara, Krimihara, Kusthahara actions most of the drugs will effectively works on Sheetapitta Samprapti Vighatana. Drugs like Haritaki, Amalaki and Pippali are having potent Rasayana properties and will helps in increasing Vyadhikshamatva of body.

Discussion

The disability and distress caused by Urticaria can lead to serious impairment of quality of life, almost comparable to that experienced by patients with cardiovascular disease. In General, a drug with Anti-inflammatory, Antibacterial, Anti allergic, Antihistaminic and Immune modulator activity will work here. While analyzing the properties of ingredients of Haridrakhanda, all the drugs have got anti-inflammatory, antimicrobial and immunomodulator actions.

According to Ayurveda, Sheetapitta is primarily affecting the Rasavaha and Raktavaha Srotas as Vata, Pitta and Kapha are vitiated and mainly Vayu is vitiated. In Udarda, mainly Kapha dosha is vitiated and In Kotha, mainly Pitta and Kapha dosha are involved. In the management of Sheetapitta, Acharya mentioned that the main aim is to alleviate the Vata. Because vitiated Vata also vitiated the Kapha dosha and both are vitiated the Pitta dosha in body and pathology of Urticaria is developed. Most of the drugs in Haridrakhanda are having the dominance of Katu, Tikta, Kashaya, Madhura Rasa, Ushna Virya, Katu and Maadhura Vipaka and Kapha Pitta / Tridosha Shamaka qualities.                          Haridrakhanda increases the Agni. Which reduce the Amadosha. Most the ingredients having Vishghna properties, thus will help in clearance of Amavisha. Goghrita and milk are enriched almost with all minerals and milk is considerable as complete food. Both these will increase the power of immune system. Most of the ingredients having Vishghna, Kandughna, Kushthaghna, Shothaghna properties that will help in Samprapti Vighatana of Sheetapitta by slow down the process of inflammation or pathogenesis. Iron/Lauha Bhasma is mainly works on Rakta Dhatu. So, Rakta Dushti Janya Vikara also subside.  As per context Tridosha involvement is there in Sheetapitta, Udarada, Kotha, therefore Tridoshahara drug should be used. As in Haridrakhanada, Haridra itself is the main ingredient and having the Tridoshashamaka property, anti-allergic, anti-inflammatory etc properties, thus it will surely overcome the pathogenesis processing in the body.

Conclusion

After analyzing the properties of each ingredient in Haridrakhanda, it can be concluded that the formulation has potent effect in curing Sheetapitta, Udarda and Kotha. 

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